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Association between asthma and risk of cardiovascular disease in Korean adults
Jihye Jung1, Jimin Sung1, Sunwoo Kim1
1Department of Medicine, College of Medicine, Chosun University, Gwangju, Republic of Korea.
Insights
Asthma diagnosis and treatment significantly increase the risk of ischemic heart disease in Korean adults. Further research is needed for cardiovascular disease (CVD) risk assessment and management in asthma patients.
Area of Science:
- Epidemiology
- Cardiology
- Pulmonology
Background:
- Cardiovascular disease (CVD) is a leading cause of mortality in Korea.
- Asthma has been linked to negative impacts on cardiovascular health.
- Understanding the association between asthma and CVD is crucial for public health.
Purpose of the Study:
- To investigate the association between asthma and cardiovascular disease (CVD) in Korean adults.
- To examine the current status, treatment, and duration of asthma in relation to CVD.
- To identify specific CVD risks associated with asthma characteristics.
Main Methods:
- Utilized data from the Korea National Health and Nutrition Examination Survey (2016-2021).
- Included 34,384 adults aged 19 years and older.
- Analyzed asthma characteristics (diagnosis, treatment, duration) and CVD outcomes (hypertension, ischemic heart disease, stroke) using chi-square and logistic regression.
Main Results:
- Asthma diagnosis (OR=2.06), treatment (OR=1.93), and long duration (OR=3.54) were significantly associated with increased risk of ischemic heart disease.
- Hypertension and stroke showed no significant correlation with asthma-related characteristics.
- Prevalence rates: Asthma (3.1% diagnosis, 1.6% current), CVD (20.2% hypertension, 2.3% ischemic heart disease, 1.8% stroke).
Conclusions:
- Asthma diagnosis and related characteristics are linked to a higher risk of ischemic heart disease.
- The findings highlight the need for focused research on cardiovascular risk assessment and management in individuals with asthma.
- This study provides valuable insights into the interplay between respiratory and cardiovascular health in the Korean population.
Objectives:
Cardiovascular disease (CVD) is a major cause of death in Korea, and studies have reported that asthma can have a negative impact on CVD. This study aimed to identify the association between asthma and CVD, including the current status, treatment status, and duration of asthma in Korean adults.
Methods:
The Korea National Health and Nutrition Examination Survey (2016-2021) was used, and 34,384 adults aged 19 years or older were included. Exposures were asthma-related characteristics, and outcomes were hypertension, ischemic heart disease, and stroke. The association between asthma characteristics and CVD was analyzed using the chi-square test and multiple logistic regression analysis.
Results:
The asthma diagnosis experience rate of the population was 3.1%; 1.6% were currently suffering from asthma, 1.0% were receiving asthma treatment, 0.6% were receiving regular medication, and 1.5% had a disease duration of 11 years or more. The CVD diagnosis rates in the population were 20.2% for hypertension, 2.3% for ischemic heart disease, and 1.8% for stroke. Compared to those who had no asthma diagnosis, those who had been diagnosed with asthma (OR = 2.06, 95% CI = 1.47-2.87), received asthma treatment (OR = 1.93, 95% CI = 1.22-3.04), and had a long duration of asthma (OR = 3.54, 95% CI = 1.71-7.33) had a significantly higher risk of ischemic heart disease. However, hypertension and stroke were not significantly correlated with asthma-related characteristics.
Conclusions:
Asthma diagnosis and asthma-related characteristics were associated with an increased risk of ischemic heart disease. Our study suggests that research on risk assessment and management of CVD in patients with asthma would be needed.
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