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Updated: May 29, 2025

Synergetic Use of Neural Precursor Cells and Self-assembling Peptides in Experimental Cervical Spinal Cord Injury
Published on: February 23, 2015
Using an acellular dermal matrix as a neuroprotective wrap-around for treating recurrent nerve entrapment syndromes:
Till Wagner1, Dietmar J O Ulrich2
1Department of Plastic and Reconstructive Surgery, Radboud University Medical Center Nijmegen (Radboudumc), Geert Grooteplein, 10, 6525 GA, Nijmegen, The Netherlands. Till.Wagner@Radboudumc.nl.
Abstract:
Recurrent nerve entrapment syndrome is a well-known complication in peripheral nerve surgery that often leads to multiple reoperations and increases the risk of unfavorable outcomes due to scarring. In our outpatient clinic, we found two patients with recurrent nerve entrapment syndrome with significant symptoms such as complete sensory loss and chronic pain who were willing to undergo re-exploration of their entrapped nerves and cover them with a human acellular dermal matrix (ADM) as a protective shield against recurrence. Both patients had complete recovery of the nerve entrapment syndrome with satisfactory clinical results. The use of a human ADM appears to be a promising tool for recurrent nerve entrapment surgery without adding morbidity to the procedure.
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