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Updated: May 29, 2025

Comparing the Effects of Electronic Cigarette Vapor and Cigarette Smoke in a Novel In Vivo Exposure System
Published on: May 24, 2017
Electronic cigarette cue reactivity in exclusive electronic cigarette users.
Ashley E Douglas1, Andrea R Milstred1, Polina Krom1
1Department of Psychology, West Virginia University, Morgantown, WV 26505, USA.
Electronic cigarette (ECIG) cues significantly increase craving and negative mood in individuals who vape. This suggests a need for restrictions on where vaping is permitted to reduce triggers.
Area of Science:
- Behavioral psychology
- Addiction research
- Public health
Background:
- Electronic cigarette (ECIG) cues can trigger cravings in smokers.
- Limited research exists on ECIG cue effects in individuals with minimal smoking history who regularly vape.
Purpose of the Study:
- To investigate the impact of ECIG cue exposure on craving, withdrawal relief anticipation, mood, and decision-making in regular vapers with minimal smoking history.
Main Methods:
- 42 participants completed within-subjects conditions with ECIG or neutral cues.
- Subjective measures of craving, withdrawal, and mood were assessed pre- and post-cue exposure.
- Delay discounting and behavioral economic tasks evaluated ECIG use after cue exposure.
Main Results:
- ECIG cues, compared to neutral cues, significantly increased ECIG craving, anticipated withdrawal relief, and negative mood.
- ECIG cues also increased discounting of delayed ECIG access (minutes), but not puffs.
Conclusions:
- This study is the first to show ECIG cues elevate craving and negative mood in non-smokers who vape.
- Findings support the need for regulations on public vaping to mitigate cue-induced urges.
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