Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Role of Hippocampus in Memory

Role of Hippocampus in Memory

The hippocampus, a critical brain structure, plays an essential role in memory processing, particularly in the formation and retrieval of memory. This small, seahorse-shaped region is located within the medial temporal lobe, with one hippocampus in each brain hemisphere. Experimental studies involving lesions in the hippocampi of rats have demonstrated significant impairments in tasks such as object recognition and maze navigation, indicating the hippocampus involvement in both recognition and...

Association Areas of the Cortex

Association Areas of the Cortex

Association areas are regions of the cerebral cortex that do not have a specific sensory or motor function. Instead, they integrate and interpret information from various sources to enable higher cognitive processes such as memory, learning, and decision-making. Some key association areas include the following:
Prefrontal Association Area: This area is located in the frontal lobe and is involved in planning, decision-making, and moderating social behavior. It connects with primary motor areas,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Resting after learning facilitates memory consolidation and reverses spatial reorientation impairments in female 3xTg-AD mice.

Journal of Alzheimer's disease : JAD·2026

Same author

Resting After Learning Facilitates Memory Consolidation and Reverses Spatial Reorientation Impairments in 'New Surroundings' in 3xTg-AD Mice.

bioRxiv : the preprint server for biology·2024

Same author

A Hippocampal-parietal Network for Reference Frame Coordination.

bioRxiv : the preprint server for biology·2024

Same author

An Integrated Platform for <i>In Vivo</i> Electrophysiology in Spatial Cognition Experiments.

eNeuro·2023

Same author

A thalamo-parietal cortex circuit is critical for place-action coordination.

Hippocampus·2023

Same author

Analysis of cell-type-specific chromatin modifications and gene expression in Drosophila neurons that direct reproductive behavior.

PLoS genetics·2021

Search research articles

Related Experiment Video

Updated: May 29, 2025

Efficiently Recording the Eye-Hand Coordination to Incoordination Spectrum

Efficiently Recording the Eye-Hand Coordination to Incoordination Spectrum

Published on: March 21, 2019

A Hippocampal-Parietal Network for Reference Frame Coordination.

Yicheng Zheng 征亦诚¹, Xinyu Zhou 周信羽², Shawn C Moseley¹

¹Department of Psychology, Program in Neuroscience, Florida State University, Tallahassee, Florida 32306.

The Journal of Neuroscience : the Official Journal of the Society for Neuroscience

|February 5, 2025

Summary

This summary is machine-generated.

The hippocampus and parietal cortex coordinate spatial navigation by processing allocentric (map-like) and egocentric (body-centered) information. This study reveals how the parietal cortex guides the hippocampus in transforming spatial memories into future actions.

Keywords:

hippocampus movement decoding multiunit activity parietal cortex spatial navigation

More Related Videos

Modeling the Functional Network for Spatial Navigation in the Human Brain

Modeling the Functional Network for Spatial Navigation in the Human Brain

Published on: October 13, 2023

Author Spotlight: Investigating the Effects of Mind-Body-Movement Practices on Brain Function

Author Spotlight: Investigating the Effects of Mind-Body-Movement Practices on Brain Function

Published on: January 26, 2024

Related Experiment Videos

Last Updated: May 29, 2025

Efficiently Recording the Eye-Hand Coordination to Incoordination Spectrum

Efficiently Recording the Eye-Hand Coordination to Incoordination Spectrum

Published on: March 21, 2019

Modeling the Functional Network for Spatial Navigation in the Human Brain

Modeling the Functional Network for Spatial Navigation in the Human Brain

Published on: October 13, 2023

Author Spotlight: Investigating the Effects of Mind-Body-Movement Practices on Brain Function

Author Spotlight: Investigating the Effects of Mind-Body-Movement Practices on Brain Function

Published on: January 26, 2024

Area of Science:

Neuroscience
Cognitive Science
Spatial Navigation

Background:

Spatial navigation relies on integrating allocentric (map-like) and egocentric (body-centered) reference frames.
The hippocampus and parietal cortex (PC) network is implicated in coordinating these frames, but the precise mechanism is unclear.

Purpose of the Study:

To elucidate the neural mechanisms by which the hippocampus and PC coordinate allocentric and egocentric spatial information for navigation and action planning.
To investigate the temporal dynamics and information flow between the hippocampus and PC during spatial memory-guided action.

Main Methods:

Utilized a spatial memory task requiring participants to remember locations and plan future actions.
Recorded neural activity and analyzed signal transformations related to allocentric locations and egocentric action representations.

Main Results:

The hippocampus encodes allocentric spatial information, while the PC encodes upcoming actions and relays them to the hippocampus.
The transformation from spatial location to action representation occurs gradually, with egocentric action signals strengthening over time.
The PC appears to initiate egocentric representations of future goal locations, which are then conveyed to the hippocampus.

Conclusions:

The parietal cortex plays a crucial role in transforming allocentric spatial memories into egocentric action plans, potentially originating egocentric signals observed in the hippocampus.
Bidirectional communication between the PC and hippocampus is essential for integrating diverse spatial reference frames (allocentric, route-based, egocentric) during navigation.