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Opportunity for early de-escalation of antibiotics in Enterobacterales bacteremia with multiplex PCR rapid diagnostic
Erin Deja1, Adam Greenfield1, Sangeeta Sastry2
1Department of Pharmacy, Virginia Commonwealth University Health System, Richmond, VA, USA.
Abstract:
Gram-negative bacteremia and antimicrobial resistance cause significant morbidity and mortality. Strategies are needed to optimize rapid and effective antimicrobial therapy with early de-escalation. In this brief, we describe the utilization of multiplex polymerase chain reaction rapid diagnostic technology for the early de-escalation of broad-spectrum antimicrobials in patients with Enterobacterales bacteremia.
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