Candida auris screening of high-risk patients: a descriptive comparison of 2 strategies

Laura Pedersen1, Aldo Barajas-Ochoa1, Kaila Cooper2

  • 1Division of Infectious Diseases, Department of Medicine, Virginia Commonwealth University, Richmond, VA, USA.

Insights

Two Candida auris screening methods showed similar positivity rates in high-risk patients. Universal infection prevention is needed as about 3% of these patients are colonized with Candida auris.

Area of Science:

  • Infectious Diseases
  • Medical Microbiology
  • Public Health

Background:

  • Candida auris is an emerging multidrug-resistant fungal pathogen.
  • High-risk patients are susceptible to Candida auris colonization and infection.
  • Effective screening strategies are crucial for controlling Candida auris transmission.

Purpose of the Study:

  • To compare the effectiveness of two Candida auris screening strategies.
  • To evaluate positivity rates between point prevalence surveys and admission screening.
  • To inform infection prevention approaches for Candida auris in healthcare settings.

Main Methods:

  • Comparison of positivity rates between point prevalence survey (PPS) and admission screening.
  • Analysis of screening data from high-risk patient populations.
  • Statistical analysis to determine the significance of observed differences.

Main Results:

  • Positivity rates for PPS and admission screening were similar (3.9% vs. 3.4%, P=1.00).
  • Approximately 3% of high-risk patients were found to be colonized with Candida auris.
  • No statistically significant difference was observed between the two screening methods.

Conclusions:

  • Both PPS and admission screening are comparable in identifying Candida auris colonization.
  • The consistent colonization rate highlights the need for universal infection prevention measures.
  • A comprehensive approach is necessary to manage Candida auris in high-risk patient populations.