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Atherosclerotic Cardiovascular Disease in Cancer Survivors: Current Evidence, Risk Prediction, Prevention, and
Arum Choi1, Subin Kim1,2, Seonji Kim1,2
1Department of Biomedical Systems Informatics, Yonsei University College of Medicine, Seoul, Korea.
Journal of Lipid and Atherosclerosis
|February 6, 2025
Summary
Cancer survivors face a higher risk of atherosclerotic cardiovascular disease (ASCVD) due to shared risk factors, cancer
Area of Science:
- Cardiology
- Oncology
- Public Health
Background:
- Cancer survivors experience improved survival rates but face elevated risks of atherosclerotic cardiovascular disease (ASCVD).
- ASCVD risk in cancer survivors is significantly higher than in the general population, necessitating targeted management strategies.
Purpose of the Study:
- To review the risk, diagnosis, and prevention of ASCVD in cancer survivors.
- To introduce and explain the "triad model" for understanding increased ASCVD risk in this population.
Main Methods:
- Literature review examining risk factors, diagnostic tools, and prevention strategies for ASCVD in cancer survivors.
- Analysis of the "triad model" components: common catalysts, cancer influence, and treatment impact.
- Discussion of diagnostic tools like coronary artery calcium scoring and prevention through monitoring and lifestyle changes.
Main Results:
- The "triad model" highlights shared risk factors, cancer's direct cardiovascular effects, and anticancer treatment impacts on ASCVD.
- Cancer survivors have a greater likelihood of developing and succumbing to ASCVD.
- Diagnostic tools and preventative measures are crucial for managing ASCVD risk in cancer survivors.
Conclusions:
- Integrated care and tailored guidelines are essential for addressing ASCVD in cancer survivors.
- Further research into prediction models and preventative strategies is vital for improving long-term outcomes.
- Addressing cardiovascular health is critical for enhancing the overall well-being of cancer survivors.
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