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Evaluating Regional Pulmonary Deposition using Patient-Specific 3D Printed Lung Models
Published on: November 11, 2020
Commissioning small fields in lung using Monte Carlo corrected film measurements
Jessica Lye1, Guangli Song2, Maddison Shaw3
1Department Radiation Oncology, Austin Health, Ballarat, Australia; School of Health and Biomedical Sciences, RMIT University, Australia.
Monte Carlo simulations offer a new method to correct film dosimetry for lung stereotactic body radiotherapy (SBRT) treatments. This improves the accuracy of dose measurements in lung tissue, crucial for precise SBRT planning.
Area of Science:
- Medical Physics
- Radiotherapy
- Dosimetry
Background:
- Current radiotherapy commissioning often measures dose in solid water, not directly in lung tissue.
- Accurate dose characterization in lung material is vital for lung stereotactic body radiotherapy (SBRT) uncertainty analysis.
- Film dosimetry in lung phantoms requires corrections for precise dose measurement.
Purpose of the Study:
- To develop and present a method for correcting film measurements in lung material for SBRT commissioning.
- To improve the accuracy of dose delivered in lung tissue compared to treatment planning system (TPS) calculations.
- To establish a generic approach for correcting small field lung measurements using Monte Carlo simulations.
Main Methods:
- Monte Carlo (MC) simulations were used to derive medium-dependent correction factors (k_med).
- Simulations accounted for differences between film calibration in water and measurement in lung material at 6 and 10 MV.
- A novel approach applies corrections as a function of isodose level for a nominal field size, simplifying the process.
Main Results:
- Central axis dose agreement improved across all field sizes, with a 7% enhancement for a 6MV 1x1 cm^2 field.
- Position-dependent corrections significantly improved gamma assessment passing rates (5%/1mm and 3%/1mm).
- Uniform central axis corrections showed minimal improvement in passing rates.
Conclusions:
- MC simulations provide a validated method for accurate dose correction in lung materials during radiotherapy.
- The presented generic, isodose-level-based correction approach enhances the accuracy of lung SBRT commissioning.
- This method allows for more reliable comparisons between film measurements and TPS dose calculations in heterogeneous lung environments.
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