Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Glassware Calibration

Glassware Calibration

Accurate calibration of glassware, such as volumetric flasks, pipettes, and burettes, is essential to ensure accurate measurements in the analytical laboratory. Calibration helps maintain consistency across measurements and prevents errors arising from inaccurate volumes.
Volumetric flasks: Volumetric flasks are designed to prepare aqueous solutions of precise volumes accurately with a calibration line on the neck. To calibrate a volumetric flask, it is important to fill it with distilled...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Erratum: 4-Chloro-curcumin. Addendum.

IUCrData·2025

Same author

13-Nitro-benzo[<i>a</i>][1,4]benzo-thia-zino[3,2-<i>c</i>]phenoxazine.

IUCrData·2024

Same author

Benzo[<i>a</i>][1,4]benzothia-zino[3,2-<i>c</i>]phenothia-zine.

IUCrData·2024

Same author

Di- and Tricyanovinyl-Substituted Triphenylamines: Structural and Computational Studies.

ACS omega·2024

Same author

Crystal structure of 1-{4-[bis-(4-methyl-phen-yl)amino]-phen-yl}ethene-1,2,2-tricarbo-nitrile.

Acta crystallographica. Section E, Crystallographic communications·2024

Same author

Multi-analyte biochip (MAB) based on all-solid-state ion-selective electrodes (ASSISE) for physiological research.

Journal of visualized experiments : JoVE·2013

Same journal

2-[(2,5-Di-methyl-phen-yl)amino]-quinoline-3-carb-oxy-lic acid.

IUCrData·2026

Same journal

20-Oxa-penta-cyclo-[15.2.1.0<sup>2,16</sup>.0<sup>3,8</sup>.0<sup>10,15</sup>]icosa-2(16),3,5,7,10(15),11,13,18-octaen-9-one.

IUCrData·2026

Same journal

(<i>E</i>)-4-Chloro-2-[(4-hy-droxy-3-meth-oxy-benzyl-idene)amino]-phenol.

IUCrData·2026

Same journal

Propyl 4-amino-benzoate.

IUCrData·2026

Same journal

1-(2,2-Di-phenyl-ethen-1-yl)tropylium perchlorate.

IUCrData·2026

Same journal

4-[4-(4-Chloro-1,2,5-thia-diazol-3-yl)phen-yl]morpholine.

IUCrData·2026

See all related articles

Search research articles

Related Experiment Video

Updated: May 4, 2026

Assay for Phosphorylation and Microtubule Binding Along with Localization of Tau Protein in Colorectal Cancer Cells

Assay for Phosphorylation and Microtubule Binding Along with Localization of Tau Protein in Colorectal Cancer Cells

Published on: October 10, 2017

4-Chloro-curcumin.

Phuong-Truc T Pham¹, Mamoun M Bader²

¹Department of Chemistry Pennsylvania State Scranton Dunmore PA 18512 USA.

|February 10, 2025

Summary

This summary is machine-generated.

This study details the crystal structure of 4-chloro-5-hydroxy-1,7-bis-(4-hydroxy-3-methoxyphenyl)hepta-1,4,6-trien-3-one. The molecule exhibits a near-planar conformation with intramolecular hydrogen bonds and forms chains in the crystal lattice via intermolecular hydrogen bonds and pi-pi stacking.

Keywords:

crystal structure curcumin derivative hydrogen bonds

More Related Videos

Author Spotlight: Exploring Photodynamic Therapy with Curcumin in a Murine Model for Oral Candidiasis

Author Spotlight: Exploring Photodynamic Therapy with Curcumin in a Murine Model for Oral Candidiasis

Published on: October 27, 2023

Author Spotlight: Eco-friendly Photoluminescent Textile Authentication with Curcumin

Author Spotlight: Eco-friendly Photoluminescent Textile Authentication with Curcumin

Published on: December 22, 2023

Related Experiment Videos

Last Updated: May 4, 2026

Assay for Phosphorylation and Microtubule Binding Along with Localization of Tau Protein in Colorectal Cancer Cells

Assay for Phosphorylation and Microtubule Binding Along with Localization of Tau Protein in Colorectal Cancer Cells

Published on: October 10, 2017

Author Spotlight: Exploring Photodynamic Therapy with Curcumin in a Murine Model for Oral Candidiasis

Author Spotlight: Exploring Photodynamic Therapy with Curcumin in a Murine Model for Oral Candidiasis

Published on: October 27, 2023

Author Spotlight: Eco-friendly Photoluminescent Textile Authentication with Curcumin

Author Spotlight: Eco-friendly Photoluminescent Textile Authentication with Curcumin

Published on: December 22, 2023

Area of Science:

Crystallography
Organic Chemistry
Molecular Structure

Background:

Understanding the three-dimensional structure of organic compounds is crucial for predicting their properties and reactivity.
Detailed structural analysis provides insights into intermolecular interactions that govern material properties.

Purpose of the Study:

To elucidate the crystal structure of 4-chloro-5-hydroxy-1,7-bis-(4-hydroxy-3-methoxyphenyl)hepta-1,4,6-trien-3-one.
To investigate the molecular conformation and intermolecular interactions in the solid state.

Main Methods:

Single-crystal X-ray diffraction analysis was employed to determine the crystal structure.
Analysis of bond lengths, bond angles, dihedral angles, and hydrogen bonding networks.

Main Results:

The title compound, C21H19ClO6, adopts a nearly planar conformation with a dihedral angle of 2.61(7)° between the terminal phenyl groups.
Three intramolecular O-H⋯O hydrogen bonds were identified within the molecule.
In the crystal lattice, molecules are arranged into [201] chains through intermolecular O-H⋯O hydrogen bonds.
Weak aromatic π-π stacking interactions were observed, with the shortest centroid-centroid separation measuring 3.7279(8) Å.

Conclusions:

The crystal structure reveals a specific arrangement of molecules driven by hydrogen bonding and π-π stacking.
The near-planar geometry and identified hydrogen bonds are key features influencing the compound's solid-state packing and potential properties.