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Updated: May 28, 2025

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Concerns about haemolysis after oxygen-ozone therapy
Mauro Martinelli1, Maurizio Maggiorotti2, Concetta Roberta Costanzo3
1Vice-president CIO3, Largo Somalia 62, 00199 Rome, Italy.
This critique questions the link between glass containers and haemolysis in oxygen-ozone therapy, citing a lack of clinical evidence and transparency in guidelines. Further research is needed for safe application.
Area of Science:
- Medical Science
- Biomedical Engineering
Background:
- A recent article suggested haemolysis as a bias in oxygen-ozone therapy, particularly with glass containers.
- Concerns exist regarding the methodology and generalizability of findings from in vitro studies.
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