[Optimal treatment modality for patients with stage-I cervical cancer]

Expansive extirpation of the uterus was performed in 726 cases of stage TIbNXMO cervical cancer. 19.3% of 600 cases of pTIb cancer showed metastatic involvement of lymph nodes. Metastases into regional lymph nodes were found to be resistant to preoperative large-fraction irradiation. The long-term results of treatment of 484 patients with pTIbNOMO cervical cancer receiving 3 different treatment modalities (operation alone, surgery + preoperative irradiation and surgery + postoperative distant irradiation) did not show any significant difference. Complications and relapse were rarer in patients who received surgery only. Therefore, expansive extirpation of the uterus unaccompanied by distant radiotherapy should be a method of choice in treatment of stage I cervical cancer (pTIbNOMO).