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Updated: May 28, 2025

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform
Published on: April 12, 2021
Two-Year Follow-Up of a Communication Intervention on Medication Adherence and Health Literacy in Kidney Transplanted
Tone K Vidnes1,2, Astrid K Wahl1,2, Marie H Larsen3
1Department of Transplantation Medicine, Oslo University Hospital, Oslo, Norway.
Background:
Patients with chronic conditions, including kidney transplanted recipients, are required to actively participate in their continuous care and maintain motivation to adhere consistently to treatment.
Objectives:
Our study aimed to test long-term effectiveness of a new health communication intervention designed to improve on medication adherence and health literacy in kidney transplant recipients 2 years following transplantation.
Design:
A randomised controlled non-blinded study was conducted between March 2020 and August 2023.
Participants:
One hundred and ninety-five kidney transplant recipients were included.
Measurements:
Primary outcomes were self-reported medication adherence, measured by the BAASIS questionnaire, and health literacy, measured by the Health Literacy Questionnaire. The response rate was 87% (170 of 195 patients).
Results:
This study showed a significant difference between groups in favour of the intervention group for medication adherence (p < 0.02) and two essential Health Literacy Questionnaire domains-'navigating the health care system' (p < 0.02) and 'having social support for health' (p > 0.03)-2 years after transplantation. Regarding health literacy, three Health Literacy Questionnaire domains showed a significant correlation with adherence: 'having sufficient information to manage health' (p < 0.04), 'having social support for health' (p < 0.04), and 'ability to understand health information well enough to know what to do' (p < 0.05).
Conclusion:
The findings in the study highlight the pivotal role of health communication in enhancing medication adherence and supporting important health literacy aspects for kidney transplant recipients.
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