Related Experiment Video
Updated: May 28, 2025

IridiumIII Luminescent Probe for Detection of the Malarial Protein Biomarker Histidine Rich Protein-II
Published on: July 7, 2015
A new quinoline-based fluorescent-colorimetric chemosensor for sensitive and selective "on-off" detection of Pb2+
Vanshika Sharma1, Srishti Dutta1, Devanand Sahu1
1Department of Chemistry, Guru Ghasidas Vishwavidyalaya Bilaspur C.G India patra29in@yahoo.co.in goutam.patra@ggu.ac.in +91 7587312992.
Abstract:
For the first time, a novel mono Schiff base of a quinoline-based reversible fluorescent-colorimetric receptor (L) has been designed for the detection of Pb2+ ions in a semi-aqueous medium. The receptor L exhibited a very good selective fluorescent-colorimetric quick on-off response when exposed to Pb2+. The colorimetric assay showed a sensitivity of 1.2 × 10-6 M, while the fluorescent assay exhibited a sensitivity of 9.9 × 10-7 M for Pb2+. A 1 : 1 stoichiometric complexation between L and Pb2+ was determined using ESI-MS spectra and Job's plot measurements. Pb2+ was successfully measured using receptor L in both real samples and in an aqueous solution of the protein bovine serum albumin, as well as in the construction of an INHIBIT-type molecular logic gate.
Related Concept Videos
Photoluminescence: Applications
Labeling DNA Probes
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...

