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Exploring DNA-6MP interactions to develop a receptor with selective binding properties

Anna Sołdatowska1, Marcin Urbanowicz1, Magdalena Urbanowicz2

  • 1Nalecz Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences, Ks. Trojdena 4 St., 02-109 Warsaw, Poland.

International Journal of Biological Macromolecules
|February 12, 2025
PubMed
Summary

Researchers identified a specific DNA sequence that selectively binds 6-mercaptopurine (6MP), a key drug metabolite. This discovery advances DNA-based biosensors for personalized medicine and therapeutic drug monitoring.

Keywords:
6-MercaptopurineDrug–DNA interactionSelective bioreceptor

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