Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Endotracheal Intubation II: Nursing Management01:17

Endotracheal Intubation II: Nursing Management

430
Endotracheal intubation is a critical procedure that can be lifesaving for many patients with respiratory distress or failure. The role of nursing in managing endotracheal tubes is pivotal, as it involves pre-intubation preparation, assisting during the procedure, and post-extubation care.
1. Nursing Care of Patients Before Intubation
Before the endotracheal intubation procedure, nurses play an essential role in ensuring the process goes smoothly. The nurses must be familiar with intubation...
430
Endotracheal Intubation I: Procedure01:15

Endotracheal Intubation I: Procedure

605
Endotracheal or ET intubation is a critical medical procedure used to secure a patient's airway, often in acute respiratory distress, apnea, upper airway obstruction, ineffective clearance of secretions, high risk for aspiration, or during general anesthesia.
The ET tube comprises various components, including a standard adaptor to attach a bag-valve-mask (BVM) or ventilator, a cuff, a pilot balloon, and radiopaque markings along its length to measure the insertion distance. The tube sizes...
605
Endotracheal Tube Extubation01:24

Endotracheal Tube Extubation

346
Endotracheal tube extubation is a critical procedure in weaning patients from mechanical ventilation. It involves physically removing the oral or nasal endotracheal (ET) tube, marking the final step in liberating a patient from ventilatory support.
Procedure
Extubation removes the endotracheal tube (ETT) from the patient on mechanical ventilation. It requires a well-coordinated, multidisciplinary approach involving physicians, nurses, respiratory therapists, and other healthcare professionals....
346
Physiological Foundation of Stress01:24

Physiological Foundation of Stress

43
Stress triggers a coordinated physiological response involving the sympathetic nervous system (SNS) and the hypothalamic-pituitary-adrenal (HPA) axis. This dual activation ensures that the body is prepared for both immediate and prolonged stress management. The process begins with the perception of a stressor. This initial phase activates the SNS, leading to the rapid release of adrenaline (epinephrine) from the adrenal glands.
Role of the Sympathetic Nervous System
Adrenaline triggers the...
43
Hypothalamic-Pituitary Axis01:37

Hypothalamic-Pituitary Axis

59.0K
The response to stress—be it physical or psychological, acute or chronic—involves activation of the Hypothalamic-Pituitary-Adrenal (HPA) axis. The HPA axis is part of the neuroendocrine system because it involves both neuronal and hormonal communication. Its function is to regulate homeostatic systems—metabolic, cardiovascular, and immune—providing the necessary means to respond to a stressor.
59.0K
Introduction to Stress and Lifestyle01:27

Introduction to Stress and Lifestyle

69
Stress is a multifaceted response to events perceived as challenging or threatening, highlighting physical, emotional, cognitive, and behavioral reactions. Physically, stress can lead to fatigue, sleep disruptions, and various health issues such as frequent colds, chest pains, and nausea. Emotionally, it can manifest as anxiety, depression, irritability, and anger triggered by both minor and major life events. Cognitively, it may result in difficulty in concentration, memory, and...
69

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Retinal organoids and stem cell therapy for vision restoration: current progress, persistent challenges, and future directions.

International immunopharmacology·2026
Same author

Hybrid amine-derived compounds as cytotoxic anticancer leads: design, synthesis, and biological evaluation.

RSC advances·2026
Same author

Bridging the gap: Integrating oxidative stress profiling with retinal imaging for precision management of diabetic retinopathy.

Experimental eye research·2026
Same author

Development and evaluation of multifunctional niosomal cream encapsulating tretinoin and integrated with hyaluronic acid and ceramides.

Naunyn-Schmiedeberg's archives of pharmacology·2026
Same author

Synthesis, and evaluation of novel low nanomolar isoindigo-based RET kinase inhibitors.

RSC advances·2026
Same author

Squilla-derived chitosan-silver/copper nanocomposites as sustainable biomaterials for targeting multidrug resistant pathogens.

Microbial pathogenesis·2026

Related Experiment Video

Updated: May 28, 2025

Author Spotlight: A Non-Intubated Video-Assisted Thoracoscopic Surgery with Multimodal Analgesia and Sevoflurane Inhalation Anesthesia
05:39

Author Spotlight: A Non-Intubated Video-Assisted Thoracoscopic Surgery with Multimodal Analgesia and Sevoflurane Inhalation Anesthesia

Published on: May 26, 2023

1.4K

Interaction between intubation and stress regarding hemodynamic and hormonal changes.

Nashwa Farouk Abd Elhafez1, Ghaleb Ali Oriquat2, Hamdi Nsairat3

  • 1Department of Anesthesia, Intensive Care Unit, and Pain Management, Faculty of Medicine, Assiut University, Assiut, Egypt.

The Journal of International Medical Research
|February 12, 2025
PubMed
Summary

Dexmedetomidine effectively reduced biochemical stress markers during endotracheal intubation, while fentanyl promoted faster post-operative recovery. Both anesthetics increased stress markers, but dexmedetomidine offered superior stress control.

Keywords:
Hemodynamic stressdexmedetomidineendotracheal intubationfentanylgeneral anesthesiastress marker

More Related Videos

Endotracheal Intubation Using a Flexible Intubation Endoscope as a Standardized Model for Safe Airway Management in Swine
04:30

Endotracheal Intubation Using a Flexible Intubation Endoscope as a Standardized Model for Safe Airway Management in Swine

Published on: August 25, 2022

3.0K
Standardized Hemorrhagic Shock Induction Guided by Cerebral Oximetry and Extended Hemodynamic Monitoring in Pigs
07:51

Standardized Hemorrhagic Shock Induction Guided by Cerebral Oximetry and Extended Hemodynamic Monitoring in Pigs

Published on: May 21, 2019

7.3K

Related Experiment Videos

Last Updated: May 28, 2025

Author Spotlight: A Non-Intubated Video-Assisted Thoracoscopic Surgery with Multimodal Analgesia and Sevoflurane Inhalation Anesthesia
05:39

Author Spotlight: A Non-Intubated Video-Assisted Thoracoscopic Surgery with Multimodal Analgesia and Sevoflurane Inhalation Anesthesia

Published on: May 26, 2023

1.4K
Endotracheal Intubation Using a Flexible Intubation Endoscope as a Standardized Model for Safe Airway Management in Swine
04:30

Endotracheal Intubation Using a Flexible Intubation Endoscope as a Standardized Model for Safe Airway Management in Swine

Published on: August 25, 2022

3.0K
Standardized Hemorrhagic Shock Induction Guided by Cerebral Oximetry and Extended Hemodynamic Monitoring in Pigs
07:51

Standardized Hemorrhagic Shock Induction Guided by Cerebral Oximetry and Extended Hemodynamic Monitoring in Pigs

Published on: May 21, 2019

7.3K

Area of Science:

  • Anesthesiology
  • Pharmacology

Background:

  • Endotracheal intubation under general anesthesia can induce significant hemodynamic and biochemical stress responses.
  • Managing this stress is crucial for patient outcomes.

Purpose of the Study:

  • To compare the efficacy of dexmedetomidine versus fentanyl in mitigating stress markers associated with endotracheal intubation.
  • To evaluate the impact of these agents on hemodynamic parameters and patient recovery.

Main Methods:

  • A prospective randomized controlled study involving 80 patients undergoing general anesthesia.
  • Patients were assigned to receive either dexmedetomidine (Group D) or fentanyl (Group F).
  • Blood samples were collected at baseline and at multiple time points post-induction and post-intubation for stress marker analysis.

Main Results:

  • Both dexmedetomidine and fentanyl increased stress markers compared to baseline after intubation.
  • Dexmedetomidine significantly reduced cortisol, norepinephrine, and lactate levels at all measured time points post-intubation.
  • Dexmedetomidine also demonstrated better control of hemodynamic parameters immediately post-intubation, while fentanyl facilitated earlier postoperative recovery.

Conclusions:

  • Dexmedetomidine is more effective in reducing biochemical stress markers and hemodynamic changes during endotracheal intubation.
  • Fentanyl, while increasing stress markers, offers the advantage of faster postoperative recovery.
  • The choice between dexmedetomidine and fentanyl may depend on the priority of stress reduction versus speed of recovery.