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Author Spotlight: Advancements in Molecular Biomarker Testing for Non-Squamous Non-Small Cell Lung Cancer
Published on: September 8, 2023
Outcomes for Emergency Presentations of Lung Cancer: A Scoping Review
Nicholas Pettit1, Marissa Vander Missen1, Andrea Noriega1
1Department of Emergency Medicine, Indiana University School of Medicine, Indianapolis Indiana.
Lung cancer diagnosed in the emergency department (ED) often presents at advanced stages, leading to higher mortality. Improved early detection and interventions are crucial for these high-risk patients.
Area of Science:
- Oncology
- Emergency Medicine
- Public Health
Background:
- Lung cancer is frequently diagnosed in emergency departments (EDs).
- EDs play a vital role in identifying lung cancer and coordinating patient care.
- Emergency presentations (EPs) represent a significant pathway for lung cancer diagnosis.
Purpose of the Study:
- To define emergency presentations (EPs) of lung cancer.
- To analyze mortality rates, cancer stage, and treatments for lung cancer diagnosed via EPs.
- To explore the heterogeneity in defining EPs of lung cancer.
Main Methods:
- A scoping review of the literature was conducted.
- 27 relevant articles were identified from an initial screening of 1338.
- Data on definitions, mortality, stage, and treatment were extracted and synthesized.
Main Results:
- Most studies originated from the UK, reporting over 270,000 lung cancer EPs.
- Patients diagnosed via EPs had higher mortality and presented at advanced stages.
- Fewer patients with EPs received surgery or radiotherapy; EP definitions were inconsistent.
Conclusions:
- Patients with undiagnosed lung cancer presenting acutely often have advanced disease and poor outcomes.
- Significant heterogeneity exists in the definition of EPs for lung cancer.
- Further research is needed to develop interventions for improving outcomes in ED patients with suspected lung cancer.
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