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Multi-Classification of Skin Lesion Images Including Mpox Disease Using Transformer-Based Deep Learning Architectures
Seyfettin Vuran1, Murat Ucan2, Mehmet Akin3
1Department of Information Technologies, Dicle University, Diyarbakir 21200, Turkey.
Diagnostics (Basel, Switzerland)
|February 13, 2025
Summary
A new deep learning model accurately diagnoses Mpox disease from skin images, offering a faster, more reliable alternative to traditional methods. This advancement aids medical professionals in early detection and decision-making for Mpox and other skin conditions.
Area of Science:
- Medical Imaging
- Artificial Intelligence
- Dermatology
Background:
- Mpox (monkeypox) is a significant global health concern, affecting 110 countries and posing a pandemic risk.
- Traditional Mpox detection methods are slow and expensive, necessitating advanced diagnostic solutions.
- There is a critical need for rapid, accurate, and autonomous methods for Mpox diagnosis using skin lesion images.
Purpose of the Study:
- To develop a multi-class, fast, and reliable autonomous diagnostic model for Mpox and other skin diseases using transformer-based deep learning.
- To evaluate the impact of self-supervised learning, self-distillation, and shifted window techniques on diagnostic accuracy.
- To leverage the Mpox Skin Lesion Dataset (Version 2.0) for training and validation.
Main Methods:
- Utilized transformer-based deep learning architectures, including Vision Transformer (ViT), Masked Autoencoders (MAE), DINO, and SwinTransformer.
- Trained and validated models on the Mpox Skin Lesion Dataset (Version 2.0).
- Investigated the efficacy of self-supervised learning, self-distillation, and shifted window techniques within transformer models.
Main Results:
- The proposed SwinTransformer architecture achieved 93.71% accuracy, outperforming other models.
- SwinTransformer demonstrated an 8% improvement in accuracy compared to the closest competitor.
- ViT, MAE, and DINO achieved accuracies of 93.10%, 84.60%, and 90.40%, respectively.
Conclusions:
- The developed deep learning model successfully diagnoses Mpox and other skin lesions with high accuracy.
- This technology can significantly support clinical decision-making for healthcare professionals.
- Findings offer valuable insights for applying transformer-based models in medical fields with limited image data.

