Thygeson's superficial punctate keratitis

A total of 54 cases of Thygeson's superficial punctate keratitis (TSPK) were studied. In our series, women were significantly more affected than men. The median age of onset for women was younger than in men. The Schirmer values were much higher than in an age and sex matched control group, but the lysozyme concentration did not differ significantly in the affected and control group. Plasma cortisol levels were within the normal limits in TSPK for both sexes but significantly higher in the female group. The serum protein and protein fractions concentration were normal.