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Cardiovascular Symposium on Perspectives in Long COVID.
Robert S Dieter1,2, Prakasha Kempaiah1,3, Elizabeth G Dieter4
1Loyola University Stritch School of Medicine, Maywood, USA.
Long COVID, a persistent condition after SARS-CoV-2 infection, causes multi-organ issues. Research is exploring its cardiovascular mechanisms and potential treatments like sulodexide.
Area of Science:
- Cardiology
- Infectious Diseases
- Virology
Background:
- Coronavirus disease (COVID) is caused by SARS-CoV-2.
- Long COVID (post-COVID syndrome) involves persistent symptoms for months after acute infection.
- Millions face chronic multi-organ complications, including cardiovascular issues.
Purpose of the Study:
- To explore the underlying cardiovascular mechanisms of Long COVID.
- To discuss potential therapeutic targets for Long COVID cardiovascular complications.
Main Methods:
- Review of current understanding of Long COVID pathophysiology.
- Discussion of findings from a symposium on cardiovascular mechanisms.
- Consideration of potential roles for immune response and viral persistence.
Main Results:
- The exact cause of Long COVID remains unclear.
- Cardiovascular complications may involve prolonged immune activation and viral persistence.
- Inflammatory biomarkers' role in post-COVID cardiovascular issues is uncertain.
Conclusions:
- Long COVID presents a significant public health challenge with multi-organ impact.
- Further research into cardiovascular mechanisms is crucial.
- Targeted therapies, such as sulodexide, show promise in preliminary studies.
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