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Handgrip strength as a potential indicator of aging: insights from its association with aging-related laboratory
Nina Kemala Sari1, Stepvia Stepvia1, Muhana Fawwazy Ilyas2
1Geriatric Division, Department of Internal Medicine, Faculty of Medicine, Dr. Cipto Mangunkusumo National Referral Hospital, Universitas Indonesia, Jakarta, Indonesia.
Introduction:
The aging process is frequently associated with a decline in functional capacity, endurance, muscle quality, and overall quality of life. Examining aging-related biomarkers often requires significant time and financial resources, underscoring the need for a straightforward and practical indicator. This study aims to investigate the association between handgrip strength and aging-related laboratory parameters in the elderly population of Indonesia.
Methods:
A cross-sectional study was conducted involving 109 participants aged 60-82 years. Handgrip strength was measured using a Jamar hydraulic hand dynamometer and Jamar PLUS+ digital dynamometer. Aging-related laboratory biomarkers were defined as those indicating physiological aging processes.
Results:
The study revealed a significant association between handgrip strength and several aging-related laboratory parameters, including leukocyte count, absolute neutrophil count, absolute lymphocyte count, neutrophil/lymphocyte ratio, and erythrocyte sedimentation rate.
Discussion:
These findings suggest that handgrip strength could serve as a cost-effective, non-invasive predictor of aging-related health status in older adults. Its practical utility highlights its potential for guiding health interventions targeting the elderly population.

