Dual device intervention for stroke prevention and bradycardia: a case report

Fulvio Cacciapuoti1, Salvatore Crispo1, Davide D'Andrea1

  • 1Department of Cardiology, "Antonio Cardarelli" Hospital, Naples.

Insights

This case study shows how left atrial appendage closure and leadless pacemakers can prevent stroke in high-risk atrial fibrillation patients. These innovative strategies manage heart rate and reduce bleeding risks without long-term anticoagulation.

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Electrophysiology

Background:

  • Atrial fibrillation increases stroke risk, often requiring anticoagulation.
  • Patients with intracranial hemorrhage history present challenges for anticoagulation and dual antiplatelet therapy.
  • Bradyarrhythmias in atrial fibrillation patients may necessitate pacing.

Purpose of the Study:

  • To present a case of managing a high-risk atrial fibrillation patient with a history of intracerebral hemorrhage.
  • To highlight the use of innovative devices for stroke prevention and heart rate control.
  • To demonstrate an alternative to long-term anticoagulation in complex cardiovascular cases.

Main Methods:

  • A 61-year-old male with permanent atrial fibrillation, recent intracerebral hemorrhage, and bradycardia underwent percutaneous coronary intervention.
  • The patient subsequently received a LAmbre™ left atrial appendage closure device and an Aveir™ leadless pacemaker.
  • This combined approach aimed to prevent thromboembolic events and manage bradycardia while avoiding anticoagulation.

Main Results:

  • Both the left atrial appendage closure and leadless pacemaker procedures were technically successful.
  • The patient was discharged in stable condition, with effective stroke risk mitigation and heart rate control.
  • The chosen strategy successfully avoided prolonged anticoagulation, addressing both cardiovascular and hemorrhagic risks.

Conclusions:

  • Left atrial appendage closure and leadless pacing offer a viable alternative for stroke prevention and heart rate management in high-risk atrial fibrillation patients.
  • These innovative device-based strategies can be safely employed in patients with contraindications to anticoagulation.
  • This case underscores the importance of tailored, multi-faceted approaches for complex cardiovascular conditions.