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Comment On: Association of serum interferon alpha-2a levels with disease severity and prognosis in systemic sclerosis

Karim Dorgham1, Maude Calixte1,2, Omaira Da Mata Jardin1

  • 1Sorbonne Université, Inserm, Centre d'Immunologie et des Maladies Infectieuses (Cimi- Paris), Paris, F-75013, France.

Rheumatology (Oxford, England)
|February 13, 2025
PubMed
Abstract

No abstract available in PubMed .

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When T cells with CD4 markers are activated, they give rise to two types of effector cells: helper T cells and regulatory T cells. Meanwhile, T cells with CD8 markers differentiate into effector cytotoxic T cells. The differentiation of CD4 T cells into helper T cell subsets, such as Th1, Th2, and Th17 cells, is dependent on the antigen type, antigen-presenting cell, and regulatory cytokines.
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