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Updated: May 28, 2025

Casting Protocols for the Production of Open Cell Aluminum Foams by the Replication Technique and the Effect on Porosity
Published on: December 11, 2014
Does the application protocol influence the masking effect of resin infiltration on MIH opacities? Systematic review
Natália de Araújo Prado1, Roberta Costa Jorge1, Rudá França Moreira1
1Department of Preventive and Community Dentistry, Faculty of Dentistry, State University of Rio de Janeiro, Boulevard Vinte e Oito de Setembro, 157, Rio de Janeiro 20551-030, Brazil; School of Dentistry, University Arthur Sá Earp Neto, Avenida Barão do Rio Branco, 1003, Petrópolis 25680-120, Brazil.
Objective:
To compile the available evidence on the effectiveness of resin infiltration in masking demarcated opacities in permanent incisors with MIH and whether modifications to the treatment protocol impact the outcome.
Data Sources And Study Selection:
This review followed PRISMA2020 and was registered in PROSPERO (CRD42023414048). Searches were performed in MedLine, LILACS, BBO, Cochrane, Web of Science, Scopus, Embase, OpenGrey, and Google Scholar, by two independent reviewers. JBI and RoB2 were used to evaluate risk of bias. R software was used to perform meta-analyses.
Results:
Eight uncontrolled, two non-randomized, and two RCTs evaluated 369 teeth in 6-31year-old participants. Six studies followed the standard resin infiltration protocol, while the others reported modifications. The meta-analysis estimated an overall proportion of total masking of 37 % (CI: 18-55). Modified protocols tended to achieve higher success rates (40 %; CI: 9-72) compared to standard protocols (30 %; CI: 17-44), though this difference was not statistically significant. The overall reduction in ΔE was 3.08 (CI: 0.74-5.42), with 1.54 (CI: 0.68-2.40) for standard protocols and 3.84 (CI: 0.80-6.89) for modified ones. Seven studies had moderate risk of bias, and three had high risk. The certainty of evidence was low due to heterogeneity (I² > 80 %) and imprecision concerns.
Conclusion:
Resin infiltration is effective in reducing the color difference between MIH opacity and normal enamel. The achievement of total masking was not significantly different between the standard and modified protocols. Heterogeneity and lack of controlled studies limit the certainty of evidence.
Clinical Significance:
This review reinforces the effectiveness of resin infiltration in reducing the color difference between MIH opacity and normal enamel. Modifications in the protocol improved the infiltration but were not enough to be significantly superior. This review contributes to the understanding of peculiarities related to the microinvasive esthetic treatment of MIH.
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