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Updated: May 28, 2025

A Precision Medicine Tool for Measurement and Monitoring of Hemoglobin S in Sickle Cell Disease Patients Receiving Transfusion Therapy
Splenic Infarction in a Patient With Sickle Cell Trait Following High-Altitude Exposure
Eian G Prohl1,2, Neel K Vaidya3
1Internal Medicine, Veterans Affairs Greater Los Angeles Healthcare System, Los Angeles, USA.
Sickle cell trait (SCT) can cause splenic infarction, even in seemingly healthy individuals. This case highlights the risk of splenic complications in SCT patients at high altitudes.
Area of Science:
- Medicine
- Hematology
- Radiology
Background:
- Sickle cell trait (SCT) is typically asymptomatic.
- However, clinical complications, such as splenic infarction, can occur.
- High altitude exposure is a known risk factor for SCT complications.
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