Related Experiment Video
Updated: Jan 16, 2026

Pre-clinical Orthotopic Murine Model of Human Prostate Cancer
Published on: August 29, 2016
Prostatic Malakoplakia as a Mimic of Prostate Cancer Progression
Michael Spiker1, Jacob D Pilley2, Neel K Vaidya3
1Internal Medicine, Veterans Affairs (VA) Greater Los Angeles, University of California, Los Angeles (UCLA), Los Angeles, USA.
Prostatic malakoplakia, a rare inflammatory condition, can mimic prostate cancer progression, especially with low PSA levels during treatment. Prompt diagnosis and antibiotic treatment led to symptom improvement in one patient.
Area of Science:
- Urology
- Pathology
- Oncology
Background:
- Prostatic malakoplakia is a rare chronic inflammatory condition.
- It can mimic prostate cancer and co-occur with prostate adenocarcinoma.
- Low PSA levels during androgen deprivation therapy (ADT) can raise concern for small cell neuroendocrine carcinoma (SCNEC).
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