Pd/NHCs-Catalyzed Denitrative/Dechlorinated N-Arylation of Nitroarenes/Chloroarenes to Hydrazine Derivatives
Xuejie Wang1, Wei Chen2, Wanzhi Chen1
1Department of Chemistry, Zhejiang University, Hangzhou, 310058, China.
Abstract:
Palladium-catalyzed denitrative/dechlorinated C-N coupling reactions of nitroaromatics/chloroarenes with hydrazines/hydrazones were performed using sterically bulky N-heterocyclic ligands (NHC=2-aryl-5-(2,4,6-triisopropylphenyl)-2,3-imidazolylidene[1,5-a]pyridines). A range of N-arylbenzophenone hydrazones/hydrazine derivatives were obtained in good to excellent yields. This protocol provides an efficient method for the preparation of hydrazones/hydrazines via C-N coupling of inexpensive nitroarenes and chloroarenes.
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