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Air Pollutants Associated Hospitalization in Pediatric Pneumonia: A National Database Analysis
Phanthila Sitthikarnkha1,2, Rattapon Uppala1,2, Leelawadee Techasatian1,2
1Department of Pediatrics, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.
Insights
Air pollution, particularly dust, is strongly linked to pediatric pneumonia hospitalizations in Thailand. Reducing exposure to pollutants like dust and black carbon is crucial for child health.
Area of Science:
- Environmental Health
- Pediatric Medicine
- Epidemiology
Background:
- Pneumonia is a major cause of childhood hospitalizations and deaths globally.
- Investigating the impact of air pollution on pediatric pneumonia is critical for public health.
Purpose of the Study:
- To examine the association between aerosol components in air pollution and pediatric pneumonia hospitalizations in Thailand.
- To quantify the risk of pneumonia hospitalization related to specific air pollutants.
Main Methods:
- An observational study analyzed data from 732,700 children under 15 hospitalized with pneumonia in Thailand (2015-2019).
- Modern-Era Retrospective analysis for Research and Application version 2 (MERRA-2) data were used for aerosol components.
- Poisson regression models adjusted for demographic and geographical factors.
Main Results:
- Dust showed the strongest association with pneumonia hospitalization incidence rate across all age groups.
- A 1 μg/m³ increase in dust levels correlated with a 13.8% increase in pneumonia hospitalizations.
- Black carbon was also associated with increased hospitalization risk, with a 21.0% rise per 1 μg/m³ increase.
Conclusions:
- A significant link exists between specific air pollutants and pediatric pneumonia hospitalizations.
- Findings underscore the need for interventions to reduce air pollution exposure for children.
- Targeted strategies are essential to mitigate the health impacts of air pollution on pediatric respiratory health.
Background:
Pneumonia ranks as a leading contributor to hospital admissions and mortality among children worldwide. This study aimed to investigate the association between aerosol components of air pollution and pediatric pneumonia hospitalization.
Methods:
Employing an observational study design, data from hospitalized children under 15 years diagnosed with pneumonia in Thailand from 2015 to 2019 were analyzed to ascertain the relationship between air pollution and health outcomes. Utilizing the Modern-Era Retrospective analysis for Research and Application version 2 (MERRA-2) data for aerosol components, and adjusting for demographic and geographical factors, using Poisson regression models.
Results:
A total of 732,700 children were hospitalized with pneumonia, with children under the age of five accounting for the majority of admissions (637,313 cases, 86.9%). Dust had the strongest association with the incidence rate ratio of hospitalization in children with pneumonia across all age groups. The incidence rate ratio was 1.288 (95% CI: 1.271-1.304, p < 0.001), 1.392 (95%CI: 1.344-1.442, p < 0.001), and 1.349 (95%CI: 1.265-1.439, p < 0.001) for children under the age of 5, 5 to under 10, and 10 to under 15, respectively. The association of hospitalization among children with pneumonia increased by 21.0% and 13.8% for each 1 μg/m3 increase in black carbon and dust levels, respectively.
Conclusion:
The findings reveal a compelling link between certain air pollutants and pediatric pneumonia hospitalization, highlighting the urgent need for targeted interventions to mitigate air pollution's adverse effects.
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