[Endovascular therapy of aorto-iliac occlusive disease]

Thomas Zeller1

  • 1Universitäts-Herzzentrum Freiburg - Bad Krozingen, Abteilung Angiologie, Universitäts-Klinikum Freiburg, Südring 15, 79189, Bad Krozingen, Deutschland. thomas.zeller@uniklinik-freiburg.de.

PubMed

Insights

Endovascular therapy is now the primary treatment for aorto-iliac occlusive disease, offering a less invasive option for intermittent claudication and erectile dysfunction. Open surgery is reserved for complex cases or failed endovascular interventions.

Area of Science:

  • Vascular Surgery
  • Interventional Cardiology
  • Endovascular Techniques

Context:

  • Aorto-iliac artery occlusive disease presents with symptoms like intermittent claudication and erectile dysfunction.
  • Endovascular therapy has advanced significantly over the past two decades.

Purpose:

  • To describe the indications, techniques, and clinical outcomes of endovascular therapy for aorto-iliac artery occlusive disease.
  • To highlight the shift towards endovascular approaches as the standard of care.

Summary:

  • Endovascular therapy is the preferred first-line treatment for aorto-iliac occlusive disease, including internal iliac artery involvement, in cases with suitable anatomy and operator experience.
  • Open surgical bypass is indicated for failed endovascular treatments or unfavorable anatomy.
  • Hybrid revascularization and endovascular treatment of internal iliac artery obstructions with drug-eluting devices are also discussed.

Impact:

  • Endovascular therapy offers a standard, less invasive treatment option for aorto-iliac occlusive disease.
  • Improved stent and stent graft technology have enhanced outcomes.
  • This approach effectively manages symptoms like hip claudication and erectile dysfunction.
Abstract

Related Concept Videos

Treatment for Pulmonary Arterial Hypertension: Prostacyclin Receptor Agonists01:23

Treatment for Pulmonary Arterial Hypertension: Prostacyclin Receptor Agonists

Prostacyclin receptor agonists are a class of therapeutic agents integral to managing pulmonary arterial hypertension (PAH). These drugs operate by mimicking the action of prostaglandin I2, or PGI2, a naturally occurring compound in the body.
These agonists bind to the IPR receptor situated on the plasma membrane of the pulmonary artery smooth muscle cells. This binding triggers a cascade of reactions known as the GS-AC-cAMP-PKA pathway. This pathway results in the relaxation of smooth muscle...
Aortic Regurgitation III: Medical Management01:25

Aortic Regurgitation III: Medical Management

Aortic regurgitation (AR) is when the aortic valve does not close or seal properly, leading to backward blood circulation from the aorta into the left ventricle during diastole. Common causes of AR include rheumatic heart disease, congenital valve defects, and aortic root dilation. Managing AR requires a multifaceted approach to alleviate symptoms, preserve left ventricular function, and address the underlying cause of the regurgitation. Patients with symptomatic AR or significant left...
Peripheral Artery Disease III: Interprofessional Care01:27

Peripheral Artery Disease III: Interprofessional Care

Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...
Aneurysm III: Interprofessional Care01:26

Aneurysm III: Interprofessional Care

Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...
Varicose Veins II: Diagnostic Studies and Interprofessional Care01:26

Varicose Veins II: Diagnostic Studies and Interprofessional Care

Varicose veins, or varicosities, develop when the valves in the veins, which control blood flow, weaken or damage. It causes blood to pool and the veins to enlarge. Understanding the clinical manifestations, diagnostic approaches, and management options for varicose veins is crucial for effective treatment and relief.Clinical manifestationsClinical manifestations of varicose veins include a heavy, achy feeling or pain after prolonged standing or sitting. This discomfort can often be relieved by...
Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...