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Addressing severe alcohol withdrawal with bromocriptine: A case series
Sayantan Chattopadhyay1, Ayan Basak1, Sukriti Mukherjee2
1Department of Psychiatry, College of Medicine and JNM Hospital, Kalyani, Nadia, West Bengal.
International Journal of Psychiatry in Medicine
|February 17, 2025
Summary
Bromocriptine effectively treated severe alcohol withdrawal syndrome in two Indian patients, showing significant symptom improvement. This offers a new therapeutic option for alcohol use disorder management.
Area of Science:
- Neuroscience
- Pharmacology
- Clinical Medicine
Background:
- Alcohol withdrawal syndrome (AWS) is a global health issue, with increasing prevalence in India due to high rates of alcohol use disorders.
- Standard benzodiazepine therapy may be insufficient for some patients with severe AWS.
- Bromocriptine is emerging as a potential adjunctive treatment for refractory AWS.
Purpose of the Study:
- To report the successful use of bromocriptine in managing severe alcohol withdrawal syndrome.
- To evaluate the efficacy of bromocriptine as an adjunctive therapy for AWS.
Main Methods:
- Case report of two patients in India experiencing severe AWS.
- Treatment with bromocriptine as an adjunctive therapy to standard care.
- Clinical assessment of Alcohol Withdrawal Symptoms.
Main Results:
- Both patients demonstrated clinically significant improvements in AWS symptoms.
- Symptom relief was observed within a relatively short treatment duration.
- Successful management of severe AWS with bromocriptine adjunctive therapy.
Conclusions:
- Bromocriptine is a valuable addition to the therapeutic armamentarium for AWS.
- Adjunctive bromocriptine can offer symptom relief and improve clinical outcomes in AWS patients.
- Bromocriptine may help address the neuropsychiatric burden associated with AWS.
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