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Medicalisation in the Post-Genomic Era: Transformations in Identity, Autonomy, and Ethics.

M Karaboue¹, G V Lacasella¹

¹Department of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy.

La Clinica Terapeutica

|February 17, 2025

Summary

Genomic knowledge transforms medicalization beyond disease, impacting identity and autonomy. Ethical frameworks are needed to balance genomic innovation with human dignity and social responsibility.

Keywords:

Autonomy Bioethics Genetic determinism Genomic knowledge Medicalisation Patient identity Post-genomic society Precision medicine Predictive medicine Social justice

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Area of Science:

Genomics and Society
Bioethics
Medical Sociology

Background:

The post-genomic era redefines medicalization, extending its reach to personal identity and societal norms.
Genomic knowledge presents both opportunities for liberation and new forms of constraint for individuals and society.

Purpose of the Study:

To examine the multifaceted implications of genomic knowledge on individual and collective experiences.
To explore the ethical challenges and societal impacts arising from genomic advancements in healthcare and research.

Main Methods:

Multidisciplinary analysis integrating perspectives from genetics, sociology, ethics, and law.
Critical examination of genomic data's intersection with social structures and healthcare practices.
Review of ethical considerations in predictive and precision medicine, including consent and genetic determinism.

Main Results:

Genomic information influences personal identity, autonomy, and societal categorization, raising concerns about equity and justice.
Healthcare professionals face ethical tensions regarding genetic determinism and patient consent.
The roles of patients and research subjects are evolving within the context of genomic medicine.

Conclusions:

Genomic innovation offers significant promise but also presents perils that require careful navigation.
Developing robust ethical frameworks is crucial to ensure scientific progress aligns with human dignity and social responsibility.
Addressing the societal impact of genomic categorization is essential for promoting equity and justice.