Dietary herbs that interact with gut microbiota: roles as anti-stroke agents

Growing evidence suggests that dietary herbs can prevent stroke by regulating the composition and structure of gut microbiota. The components of dietary herbs can also be metabolized or converted into bioactive molecules for treating stroke by gut microbiota, and exert therapeutic effects by inhibiting inflammation, oxidative stress, apoptosis, and other processes caused by stroke. A deep understanding of the mechanism of gut microbiota-mediated dietary herbal intervention in stroke is of great significance for the treatment and drug screening of stroke diseases. In this review, we summarise the complex bidirectional relationship between stroke and gut microbiota and provide a detailed introduction to the mechanism of the interaction between dietary herbs and gut microbiota in intervening in stroke. In addition, we also discuss the limitations of current research and potential directions in this field, hoping to provide ideas and references for the treatment and drug development of stroke diseases.

Dietary herbs and active ingredients can balance the intestinal microbiota disorders in stroke patients or models, and herbal ingredients can be converted into more easily absorbed active substances under the action of microorganisms, thereby exerting therapeutic effect on stroke diseases.