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Minimally-invasive common-path OCT system for neurosurgery applications.

Gary Evans1,2, Jerome Gandar2, Simon Thiele3

  • 1Clee Medical, Geneva, Switzerland.

Biomedical Optics Express
|February 17, 2025
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Summary

We developed a new optical coherence tomography (OCT) system for neurosurgery. This real-time imaging tool aids in precise surgeries and reduces hemorrhage risk.

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Area of Science:

  • Medical Imaging
  • Neurosurgery
  • Biomedical Engineering

Background:

  • Minimally-invasive neurosurgery requires advanced imaging for accuracy.
  • Current techniques may have limitations in real-time tissue identification and hemorrhage detection.

Purpose of the Study:

  • To develop and evaluate a novel common-path optical coherence tomography (OCT) system for neurosurgical applications.
  • To assess the system's real-time 3D imaging, tissue identification, and blood flow detection capabilities.

Main Methods:

  • A common-path OCT system operating at 1310 nm was designed.
  • A novel forward-viewing monolithic endoscope was integrated for neurosurgical use.
  • The system was tested in vivo using a rabbit cohort.

Main Results:

  • The system demonstrated real-time 3D imaging capabilities.
  • Effective real-time tissue identification was achieved.
  • Blood flow detection was successfully demonstrated, indicating potential for hemorrhage risk reduction.

Conclusions:

  • The developed OCT system offers a promising tool for enhancing neurosurgical accuracy.
  • Real-time imaging and tissue identification can improve stereotactic procedures like deep brain stimulation and biopsy.
  • The system's blood flow detection capability may significantly mitigate surgical hemorrhage risks.