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Updated: May 27, 2025
Invasive Hemodynamic Characterization of the Portal-hypertensive Syndrome in Cirrhotic Rats
Published on: August 1, 2018
CROATIAN GUIDELINES FOR THE DIAGNOSIS AND TREATMENT OF PORTAL HYPERTENSION
Ivica Grgurević1,2, Tajana Filipec Kanižaj3, Hrvoje Iveković4
1Department of Gastroenterology, Hepatology and Clinical Nutrition, Dubrava University Hospital, University of Zagreb School of Medicine, Zagreb, Croatia.
Insights
New guidelines address portal hypertension (PH), a serious complication of cirrhosis and liver disease. These recommendations aim to improve patient care by standardizing diagnosis and treatment strategies for PH.
Area of Science:
- Hepatology
- Gastroenterology
- Clinical Medicine
Background:
- Liver diseases are a major global health concern, with cirrhosis being a leading cause of death in Europe.
- Cirrhosis progression leads to severe complications including portal hypertension (PH), liver failure, and hepatocellular carcinoma.
- Portal hypertension is a critical factor in chronic liver disease advancement and a predictor of mortality in cirrhosis patients.
Purpose of the Study:
- To present a condensed version of the Croatian national guidelines for portal hypertension (PH).
- To highlight key recommendations for the classification, diagnosis, and treatment of PH.
- To enhance the care of patients suffering from chronic liver disease and its complications.
Main Methods:
- Development of national guidelines by the Croatian Society of Gastroenterology working group.
- Discussion and agreement on guidelines during 2023.
- Incorporation of recent data and the Baveno VII consensus.
Main Results:
- Establishment of updated recommendations for portal hypertension management.
- Focus on standardized classification, diagnosis, and treatment strategies.
- Aimed at improving clinical outcomes for patients with cirrhosis and PH.
Conclusions:
- National guidelines are essential for optimizing the care of patients with portal hypertension.
- The presented recommendations reflect the latest advancements and consensus in the field.
- Adoption of these guidelines is crucial for improving patient management and prognosis.
Abstract:
Liver diseases are currently the eleventh leading cause of global mortality, and cirrhosis holds the ninth position among the causes of death in Europe. The progression of cirrhosis gives rise to complications such as portal hypertension (PH), liver failure, and development of hepatocellular carcinoma. PH plays a pivotal role in the advancement of chronic liver disease and stands as an independent predictor of mortality in individuals with cirrhosis. Given the numerous updates in the classification, diagnosis, and treatment strategies for PH, the adoption of national guidelines has become imperative to enhance the care of this patient population. In the wake of Baveno VII consensus, as well as the recently published data, the working group of the Croatian Society of Gastroenterology drafted the guidelines that were discussed and agreed during 2023. Herein, we present a condensed version highlighting the key recommendations.
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