Reducing prematurity-related neonatal mortality: a quality improvement project in Gandhi Memorial Hospital, Addis

Biniam Yohannes Wotango1, Wubet Mihretu Workneh2, Tariku Deressa Abdana2

  • 1Gandhi Memorial Hospital, Addis Ababa, Ethiopia biniamy50@gmail.com.

BMJ Open Quality
|February 17, 2025
PubMed

Insights

Neonatal deaths due to prematurity were reduced by 25.6% at Gandhi Memorial Hospital. Interventions included CPAP transport, enhanced CPAP device use, and infection control, significantly improving infant survival rates.

Area of Science:

  • Neonatal care
  • Quality improvement in healthcare
  • Public health

Background:

  • Neonatal deaths constitute nearly 50% of global under-five child mortality.
  • Preterm birth is the leading cause of neonatal mortality, leading to complications like respiratory distress syndrome and sepsis.
  • Gandhi Memorial Hospital faced a high neonatal mortality rate, with 57.7% of deaths linked to prematurity-related issues and a 20.7% baseline mortality for premature neonates in the NICU.

Purpose of the Study:

  • To decrease neonatal mortality associated with prematurity at Gandhi Memorial Hospital.
  • To implement and evaluate targeted interventions to improve outcomes for premature infants.

Main Methods:

  • A multidisciplinary team utilized a fishbone diagram to identify causes of prematurity-related neonatal deaths.
  • The Institute for Healthcare Improvement (IHI) model, incorporating Plan-Do-Study-Act cycles, guided the quality improvement process.
  • Key interventions included CPAP transport for neonates, enhanced use of CPAP devices with integrated oxygen systems, and implementation of a four-component infection prevention checklist.

Main Results:

  • The implementation of three interventions led to a 25.6% reduction in prematurity-related neonatal mortality.
  • Run chart analysis demonstrated a statistically significant decrease in mortality rates, shifting below the baseline median.

Conclusions:

  • The quality improvement project successfully reduced prematurity-related neonatal deaths at Gandhi Memorial Hospital through targeted interventions.
  • Recommendations include standardizing CPAP transport protocols, optimizing CPAP device usage in NICUs, and ensuring full implementation of infection prevention checklists to enhance neonatal outcomes.
Abstract