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Association between cardiovascular health and overactive bladder.
Zehao Li1, Xiangliang Liu1, Yuguang Li1
1Cancer Center, The First Hospital of Jilin University, Changchun, China.
Scientific Reports
|February 17, 2025
Summary
Improving cardiovascular health through Life's Essential 8 (LE8) metrics, including diet and exercise, is linked to a lower risk of overactive bladder (OAB). Better LE8 scores may offer protection against OAB symptoms.
Area of Science:
- Cardiovascular Health
- Urology
- Public Health
Background:
- Lifestyle factors influence overactive bladder (OAB) risk.
- Life's Essential 8 (LE8) is a composite metric for cardiovascular health.
- The relationship between LE8 and OAB is not well understood.
Purpose of the Study:
- To investigate the association between Life's Essential 8 (LE8) scores and overactive bladder (OAB) prevalence.
- To explore the correlation between cardiovascular health metrics and OAB risk.
Main Methods:
- Analysis of 23,187 participants from the National Health and Nutrition Examination Survey (NHANES) (2005-2018).
- Stratification into low, moderate, and high LE8 score groups.
- Logistic regression, restricted cubic splines (RCS), and weighted quantile sum (WQS) regression were used to analyze the association.
Main Results:
- Higher LE8 scores were significantly associated with a reduced risk of OAB.
- This inverse correlation remained consistent after adjusting for covariates.
- Glycemic control within LE8 demonstrated the most substantial contribution to this protective effect.
Conclusions:
- Optimizing cardiovascular health, as measured by LE8, may be a protective strategy against overactive bladder (OAB).
- LE8 metrics, particularly glycemic control, show potential for novel OAB prevention approaches.
- Further research into lifestyle interventions for OAB prevention is warranted.
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