Disease associated malnutrition in pediatrics - what is new?

Koen Huysentruyt1, Jessie M Hulst2,3, Konstantinos Gerasimidis4

  • 1Department of Pediatric Gastroenterology, UZ Brussel, Vrije Universiteit Brussel (VUB), Brussels, Belgium.

Insights

Disease-associated malnutrition (DAM) in children requires comprehensive assessment integrating anthropometrics and clinical evaluation. Nutritional support for critically ill children must be individualized, with intermittent feeding potentially offering benefits but needing careful management.

Area of Science:

  • Pediatric critical care medicine
  • Clinical nutrition
  • Childhood disease management

Background:

  • Disease-associated malnutrition (DAM) is a significant challenge in hospitalized and chronically ill children.
  • Recent literature (post-2023) provides updated insights into DAM management.
  • Understanding DAM is crucial for improving pediatric patient outcomes.

Purpose of the Study:

  • To review the latest research on the prevalence, assessment, and treatment of DAM in pediatric populations.
  • To synthesize findings on nutritional assessment methods and their correlation with clinical outcomes.
  • To evaluate current strategies for nutritional support in critically ill children.

Main Methods:

  • Systematic review of pediatric literature published since 2023.
  • Analysis of studies on DAM prevalence, sarcopenia assessment, and clinical outcomes.
  • Examination of research on nutritional management in critically ill children, including feeding strategies.

Main Results:

  • DAM prevalence is influenced by multiple factors, with varied assessment methods showing links to sarcopenia and outcomes.
  • Nutritional management strategies are being explored in relation to metabolic changes in critically ill children.
  • Feeding intolerance, enteral nutrition barriers, and feeding schedules (continuous vs. intermittent) are key research areas.

Conclusions:

  • A comprehensive approach combining anthropometrics, nutritional history, and physical examination is recommended for assessing malnutrition, frailty, and sarcopenia in pediatric patients.
  • Nutritional support for critically ill children requires tailored strategies aligned with illness phases.
  • Intermittent feeding shows promise for ketosis and circadian rhythm alignment but necessitates vigilant monitoring to avoid nutritional deficits.
Abstract

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