Disease associated malnutrition in pediatrics - what is new?
Koen Huysentruyt1, Jessie M Hulst2,3, Konstantinos Gerasimidis4
1Department of Pediatric Gastroenterology, UZ Brussel, Vrije Universiteit Brussel (VUB), Brussels, Belgium.
Insights
Disease-associated malnutrition (DAM) in children requires comprehensive assessment integrating anthropometrics and clinical evaluation. Nutritional support for critically ill children must be individualized, with intermittent feeding potentially offering benefits but needing careful management.
Area of Science:
- Pediatric critical care medicine
- Clinical nutrition
- Childhood disease management
Background:
- Disease-associated malnutrition (DAM) is a significant challenge in hospitalized and chronically ill children.
- Recent literature (post-2023) provides updated insights into DAM management.
- Understanding DAM is crucial for improving pediatric patient outcomes.
Purpose of the Study:
- To review the latest research on the prevalence, assessment, and treatment of DAM in pediatric populations.
- To synthesize findings on nutritional assessment methods and their correlation with clinical outcomes.
- To evaluate current strategies for nutritional support in critically ill children.
Main Methods:
- Systematic review of pediatric literature published since 2023.
- Analysis of studies on DAM prevalence, sarcopenia assessment, and clinical outcomes.
- Examination of research on nutritional management in critically ill children, including feeding strategies.
Main Results:
- DAM prevalence is influenced by multiple factors, with varied assessment methods showing links to sarcopenia and outcomes.
- Nutritional management strategies are being explored in relation to metabolic changes in critically ill children.
- Feeding intolerance, enteral nutrition barriers, and feeding schedules (continuous vs. intermittent) are key research areas.
Conclusions:
- A comprehensive approach combining anthropometrics, nutritional history, and physical examination is recommended for assessing malnutrition, frailty, and sarcopenia in pediatric patients.
- Nutritional support for critically ill children requires tailored strategies aligned with illness phases.
- Intermittent feeding shows promise for ketosis and circadian rhythm alignment but necessitates vigilant monitoring to avoid nutritional deficits.
Purpose Of Review:
Disease associated malnutrition (DAM) remains an important concern in the care of hospitalized children and children with a chronic disease. This review focused on pediatric literature published since 2023 on the prevalence, assessment and treatment of DAM in different settings.
Recent Findings:
The prevalence of DAM depends on a variety of factors. Studies focused on the relationship between different assessment methods of DAM and sarcopenia in hospitalized children and children with an underlying disease and clinical outcomes. Several papers focused on exploring the interplay between nutritional management and the evolving metabolic phases of critically ill children. Some studies explored feeding intolerance and barriers to administering enteral nutrition, micronutrient assessment and whether continuous versus intermittent feeding was superior in pediatric intensive care.
Summary:
In hospitalized children and chronically ill children, nutritional assessment and assessment of frailty and/or sarcopenia is best done using a comprehensive approach integrating anthropometrics, nutrition focused history and physical examination. Adequate nutritional support for critically ill children is challenging and needs to be tailored to the specific phases of critical illness. Intermittent feeding may offer potential advantages in inducing ketosis and circadian rhythm alignment but requires careful management to prevent nutritional deficits.
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