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Related Experiment Video

Updated: May 27, 2025

A Method for Targeted 16S Sequencing of Human Milk Samples

A Method for Targeted 16S Sequencing of Human Milk Samples

Published on: March 23, 2018

Bioactive compounds in human milk.

Ariadna Witte Castro¹, Maria Sanchez-Holgado, Miguel Saenz de Pipaon

¹Department of Neonatology. La Paz University Hospital. Hospital La Paz. Institute for Health Research-IdIPAZ. Madrid, Spain.

Current Opinion in Clinical Nutrition and Metabolic Care

|February 18, 2025

Summary

Human milk contains bioactive compounds that significantly benefit infant health, reducing disease risk. Understanding these nutrients can improve infant feeding and formula development for long-term health outcomes.

Keywords:

bioactive compounds breastmilk infant nutrition microbiota oligosaccharides

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Area of Science:

Nutritional Science
Pediatrics
Immunology

Background:

Human milk is recognized as the optimal nutrition for infants.
Breastfeeding offers numerous short- and long-term health benefits to infants.

Purpose of the Study:

To review recent research on human milk compounds and their health effects.
To understand the role of bioactive nutrients in infant health and development.

Main Methods:

Literature review of recent scientific advances.
Analysis of studies on human milk composition and infant health outcomes.

Main Results:

Bioactive compounds in human milk, including oligosaccharides, hormones, lipids, cells, and microbes, are crucial for infant health.
These compounds help reduce the risk of infectious, metabolic, and autoimmune diseases in infants.
Research is ongoing to fully elucidate the transmission mechanisms and biological effects of these compounds.

Conclusions:

Findings can inform maternal and infant interventions and modulate human milk composition.
Improvements in infant formula development and nutritional plans are potential outcomes.
Identification and isolation of human milk bioactive compounds may lead to novel supplementation strategies.