Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Nitrogen balance studies in aging rats.

J K Baldwin, P Griminger

    Experimental Gerontology
    |January 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Older rats require more dietary nitrogen and indispensable amino acids than mature rats for optimal protein utilization. This study reveals age-related differences in nutrient needs, impacting nutritional strategies for aging populations.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Towards performing high-resolution inelastic X-ray scattering measurements at hard X-ray free-electron lasers coupled with energetic laser drivers.

    Journal of synchrotron radiation·2022
    Same author

    Heterogeneous to homogeneous melting transition visualized with ultrafast electron diffraction.

    Science (New York, N.Y.)·2018
    Same author

    Cr incorporated phase transformation in Y<sub>2</sub>O<sub>3</sub> under ion irradiation.

    Scientific reports·2017
    Same author

    What determines the interfacial configuration of Nb/Al<sub>2</sub>O<sub>3</sub> and Nb/MgO interface.

    Scientific reports·2016
    Same author

    Data audit as a management tool.

    Accountability in research·2016
    Same author

    Mediation of phorbol ester-induced oxidant generation in murine epidermal cells by protein kinase C.

    Toxicology in vitro : an international journal published in association with BIBRA·2010
    Same journal

    Sit-to-stand power shows greater magnitude associations with radial bone strength compared to handgrip strength in adults aged 60-95 years: A cross-sectional study.

    Experimental gerontology·2026
    Same journal

    Impact of simultaneous motor-cognitive training on motor capacities in older adults: A quasi-randomized parallel controlled trial.

    Experimental gerontology·2026
    Same journal

    Triglyceride-glucose-related metabolic indices, phenotypic aging, and incident pulmonary embolism.

    Experimental gerontology·2026
    Same journal

    A comparative study reveals distinct patterns of resting-state activity in tinnitus and chronic pain.

    Experimental gerontology·2026
    Same journal

    Letter to the editor: Bidirectional associations between metabolic syndrome and epigenetic age acceleration.

    Experimental gerontology·2026
    Same journal

    Integrated single-cell and Mendelian randomization analyses identify aging-induced brain endothelial SPARCL1 deficiency as a key driver of vascular dementia.

    Experimental gerontology·2026
    See all related articles

    Area of Science:

    • Gerontology
    • Nutritional Biochemistry
    • Animal Nutrition

    Background:

    • Aging is associated with physiological changes that can affect nutrient metabolism and requirements.
    • Understanding age-related differences in protein and amino acid needs is crucial for maintaining health and function in older animals.

    Purpose of the Study:

    • To compare the nitrogen balance and protein requirements between aged (24-month-old) and mature (12-month-old) rats.
    • To investigate potential age-related differences in the need for indispensable amino acids.

    Main Methods:

    • Nitrogen balance studies were performed using a counter-balanced dietary sequence over four weeks.
    • Rats were fed four different diets with varying levels of casein protein and amino acid mixtures.
    • Food and nitrogen intake were monitored, and nitrogen balance was calculated.

    Related Experiment Videos

    Main Results:

    • Aged rats exhibited lower food and nitrogen intake compared to mature rats.
    • Mean nitrogen balance was lower in aged rats, indicating reduced nitrogen retention.
    • Calculations suggested an increased requirement for nitrogen and indispensable amino acids in aged rats for nitrogen equilibrium.

    Conclusions:

    • Aging in rats is associated with an increased net requirement for nitrogen and indispensable amino acids.
    • These findings highlight age-related shifts in protein metabolism and nutritional needs.
    • The results have implications for formulating diets to support the nutritional status of aging animals.