Related Experiment Video
Updated: Jul 27, 2026

Intrarenal Injection of Escherichia coli in a Rat Model of Pyelonephritis
Published on: July 18, 2017
Acute Epididymo-Orchitis Caused by Escherichia coli in a Rhesus Monkey
Heling Li1,2, Long Zhang3, Hong Wang1,2
1State Key Laboratory of Primate Biomedical Research, Institute of Primate Translational Medicine, Kunming University of Science and Technology, Kunming, China.
Abstract:
Epididymo-orchitis is characterized by painful swelling and inflammation of the epididymis and testes. A 4-year-old male rhesus monkey has clinical manifestations including anorexia, weakness, as well as redness and swelling of the right testis and epididymis. Bacterial culture of the urine was positive for Escherichia coli. Due to the antibiotic treatment being ineffective, the animal underwent a right orchiectomy. Postoperative histopathology confirmed necrosis and significant inflammatory cell infiltration, indicating severe acute epididymo-orchitis (EO) caused by E. coli infection in the rhesus monkey. After surgical treatment and postoperative care, the animal survived. To our knowledge, this represents the first report of acute EO caused by E. coli in a rhesus monkey. These findings not only enhance our understanding of EO in NHPs but also provide a reference for further biomedical studies of EO induced by E. coli.
Related Concept Videos
Rheumatic Heart Disease I: Introduction
Rocky Mountain Spotted Fever
Bacterial Meningitis
Respiratory Syncytial Virus Disease
Cryptococcal Meningitis
Bacterial Meningitis I: Introduction

