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Updated: Jan 19, 2026

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Facilitating high throughput collections-based genomics: a comparison of DNA extraction and library building methods

William A Marsh1, Andie Hall2, Ian Barnes2

  • 1Natural History Museum, Cromwell Road, South Kensington, SW7 5BD, London, UK. w.marsh@nhm.ac.uk.

Scientific Reports
|February 19, 2025
PubMed
Summary

DNA barcoding for conservation relies on reference libraries. The Santa Cruz Reaction (SCR) method efficiently retrieves degraded DNA from museum specimens, enabling high-throughput, low-cost library construction for broader scientific use.

Keywords:
BiodiversityHistorical DNAMuseomicsMuseum collections

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