A complicated case of ciliary body melanoma and glaucoma

This clinicopathological case report describes the bilateral ocular pathology in an elderly man suffering from primary open angle glaucoma, aphakia and a ciliary body melanoma which was treated by cryotherapy to preserve vision in the better eye. Liver metastases were detected 18 months after the tumour was recognised. At autopsy, melanoma metastases were found within a renal cell carcinoma which had also metastasised to the lungs. Other abnormalities included aphakic maculopathy, senile macular degeneration, asteroid hyalosis and patchy hyalinisation of the retinal vasculature, which in one eye was the source of preretinal neovascularisation derived from intramural neovascularisation.