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Acute Pharyngitis01:30

Acute Pharyngitis

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Introduction
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
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Acute pharyngitis can be categorized based on its underlying cause:
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Acute Pancreatitis II: Clinical Manifestations and Management01:30

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Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...
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Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
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Pneumonia III: Complications and Assessment01:30

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Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
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Increased Body Temperature01:25

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A body temperature above  38°C  (100.4 °F) is known as fever or pyrexia, and a person with fever is termed 'febrile.' Typically, the hypothalamus, a part of the brain that acts as the body's thermostat, regulates body temperature through a thermoregulatory setpoint. It receives signals from cold and warm thermal receptors throughout the body and adjusts the body's temperature accordingly. Fever occurs when this hypothalamic setpoint is altered, usually in...
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Updated: May 27, 2025

Preparation of Mouse Pituitary Immunogen for the Induction of Experimental Autoimmune Hypophysitis
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Acute hypophysitis with pachymeningitis.

Mayank Sahu1, Debabrata Chakraborty2, Suddhasatwya Chatterjee1

  • 1Internal Medicine, Apollo Multispeciality Hospital, Kolkata, West Bengal, India.

BMJ Case Reports
|February 20, 2025
PubMed
Summary
This summary is machine-generated.

A rare case of IgG4-related hypophysitis and pachymeningitis presented as common symptoms like headache and fever. Prompt diagnosis requires broad clinical suspicion for uncommon conditions.

Keywords:
Headache (including migraines)ImmunologyInfection (neurology)Pituitary disordersTB and other respiratory infections

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Area of Science:

  • Neurology
  • Endocrinology
  • Immunology

Background:

  • Common symptoms like headache, fever, and neck stiffness can mask rare underlying conditions.
  • Diagnostic challenges arise when initial presentations mimic more prevalent diseases.

Purpose of the Study:

  • To report a case of IgG4-related hypophysitis and pachymeningitis presenting with non-specific symptoms.
  • To highlight the importance of maintaining a high index of suspicion for rare diagnoses.

Main Methods:

  • Case report of an elderly woman with new-onset neck stiffness, headache, and fever.
  • Systematic diagnostic workup to identify the cause of symptoms.

Main Results:

  • The diagnostic process ultimately identified IgG4-related hypophysitis and pachymeningitis.
  • Initial common differentials, including tuberculosis, were considered but ruled out.

Conclusions:

  • Uncommon diagnoses like IgG4-related hypophysitis and pachymeningitis require prompt clinical suspicion.
  • A thorough and timely diagnostic workup is crucial for identifying complex and rare conditions presenting with overlapping symptoms.