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Modeling forebrain regional development and connectivity by human brain organoids

Mu Seog Choe1, Cynthia Lo1, In-Hyun Park1

  • 1Interdepartmental Neuroscience Program, Department of Genetics, Yale Stem Cell Center, Yale Child Study Center, Wu Tsai Institute, Yale School of Medicine, New Haven, CT, United States.

Current Opinion in Genetics & Development
|February 21, 2025
PubMed
Summary

Modeling human forebrain development using organoids is crucial for understanding human cognition and disease. This review covers developmental biology and diverse organoid modeling methods for the forebrain.

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