The Curing Coma Campaign: A platform for advancing science and clinical care worldwide

Recovery from coma or impaired consciousness is often the central issue in acute neurologic conditions such as traumatic brain injury, hypoxic-ischemic brain injury, stroke, and central nervous system infections. Recent advances in the science underpinning acute disorders of consciousness (DoC) have also served to highlight further scientific gaps and the lack of a coordinated approach to improving care for these patients. The Curing Coma Campaign (CCC) was initiated by the Neurocritical Care Society in 2019 as a platform to bring together the scientific, clinical, and public communities to cohesively address this issue. Comprised of various modules and working groups focused on aspects including fundamental science, prospective clinical studies, ethics, care of the coma patient, and engagement and community, initial efforts of the CCC have ranged from developing strategies for biomarker development to creating World Coma Day as an opportunity for widespread interaction. To achieve the goal of relevance across different geographic and resourced environments, the CCC implemented specific considerations to ensure equity and generalizability. These include international representation of patients in research studies, attention to assessments and interventions that can be implemented in resource-limited settings, and recognition of the impact of culture on the care of DoC patients.