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Walking the tightrope: toward clinical equipoise in portal vein thrombosis

Lawrence R Schiller1

  • 1Department of Internal Medicine, Baylor University Medical Center and Texas A&M College of Medicine, Dallas Campus, Dallas, Texas, USA.

Proceedings (Baylor University. Medical Center)
|February 24, 2025
PubMed
Abstract

No abstract available in PubMed .

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Esophageal varices often manifest as gastrointestinal bleeding episodes, presenting symptoms like hematemesis (vomiting of blood), hematochezia (passing fresh blood via the rectum), and melena (black, tarry stools). Other signs can include weight loss, anorexia, abdominal discomfort, jaundice, pruritus, altered mental status, and muscle cramps.
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Esophageal varices are dilated, tortuous veins which are found mainly in the submucosa of the lower esophagus but which may also appear higher up or extend into the stomach. They develop due to increased pressure in the portal venous system, often as a result of liver cirrhosis. This condition scars and damages the liver, impeding normal blood flow through the portal vein. To compensate, blood seeks alternative pathways, forming fragile new vessels (varices) in the esophagus and stomach. These...
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