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Advanced Stage Head and Neck Cancer Diagnosis: HEADSpAcE Consortium Health Systems Benchmarking Survey
Grant Creaney1,2, Mariél de Aquino Goulart1,2, Alex McMahon1
1School of Medicine, Dentistry and Nursing, University of Glasgow, Glasgow, UK.
Head & Neck
|February 25, 2025
Summary
Implementing formal referral triage, routine monitoring, and public funding in health systems can reduce advanced-stage head and neck cancer (HNC) diagnoses. These factors are key to improving early detection and patient outcomes.
Area of Science:
- Oncology
- Health Services Research
- Public Health
Background:
- Most head and neck cancer (HNC) patients are diagnosed at advanced stages globally.
- The influence of health system factors on HNC diagnostic stage requires further investigation.
Purpose of the Study:
- To investigate the association between health system factors and the proportion of advanced-stage head and neck cancer diagnoses.
- To identify modifiable health system factors that could improve early HNC detection.
Main Methods:
- A survey of 18 head and neck cancer (HNC) centers within the HEADSpAcE Consortium.
- Analysis using least square means to compare health system factors with the proportion of advanced-stage HNC.
Main Results:
- Formal referral triaging was associated with a 14% lower proportion of advanced-stage HNC.
- Routine monitoring of referral-to-diagnosis time was linked to a 16% decrease.
- Fully publicly funded systems showed a 17% reduction in advanced-stage diagnoses.
Conclusions:
- Health system factors like referral triaging, monitoring, and public funding are associated with lower advanced-stage HNC rates.
- Identifying and monitoring these factors can inform interventions and system redesign for earlier HNC diagnosis.
- Further research is needed to address health systems where data on these factors is not routinely available.

