Related Experiment Video
Updated: May 26, 2025

06:15
Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
1.0K
Keloid Excision With Primary Closure Combined With Superficial Radiation Therapy (SRT-100).
Sheng-Lin Tsai1, Yu-Chi Tsai1, Yu-Tse Weng1
1From the Division of Plastic and Reconstructive Surgery, Department of Surgery.
Annals of Plastic Surgery
|February 25, 2025
Summary
Superficial radiation therapy (SRT) after keloid excision with primary closure effectively prevents recurrence and improves scar appearance. This treatment offers a safe and satisfactory option for keloid management, minimizing side effects like hyperpigmentation.
Area of Science:
- Dermatology
- Oncology
- Plastic Surgery
Background:
- Keloid treatment often involves surgery and radiotherapy to reduce recurrence.
- Radiotherapy side effects are a concern, making superficial radiation therapy (SRT) a potentially safer alternative due to its targeted skin approach.
- Previous studies suggest good outcomes with surgery and SRT for keloids.
Purpose of the Study:
- To evaluate the efficacy and safety of keloid excision with primary closure followed by SRT in Taiwanese patients.
- To assess recurrence rates and scar improvement using the Vancouver Scar Scale (VSS).
Main Methods:
- A retrospective study of 12 patients with 16 keloids treated with excision and primary closure.
- Postoperative treatment included 2 or 3 fractions of SRT on days 0, 1, and 2.
- Data collected included preoperative and 2-month postoperative VSS scores, recurrence, and side effects.
Main Results:
- The mean VSS score significantly improved from 8.69 preoperatively to 3.56 at 2 months postoperatively.
- No keloid recurrence was observed in patients followed for over 6 months.
- The main side effect noted was hyperpigmentation of the surrounding skin.
Conclusions:
- Combining keloid excision with primary closure and postoperative SRT is an effective treatment strategy.
- This approach leads to good cosmetic outcomes with no recurrence and patient satisfaction.
- SRT offers a reduced risk of complications, such as hyperpigmentation, compared to traditional radiotherapy.

