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Prevalence and features of coronary ectasia: an angiographic study

Esma Cetinkaya1, Fahri Er2, Senem Şaş3

  • 1Department of Cardiology, Agri Training and Research Hospital, Agri, Türkiye - es_ma_arslan@hotmail.com.

Minerva Cardiology and Angiology
|February 25, 2025
PubMed

Insights

Atherosclerosis in coronary arteries is linked to diabetes, hypertension, and kidney disease. Ectasia shows no specific risk factors, but vasculitis and musculoskeletal diseases are more common.

Area of Science:

  • Cardiology
  • Vascular Biology
  • Medical Research

Background:

  • Coronary artery morphology changes over time, including atherosclerosis and ectasia.
  • Understanding factors influencing these changes is crucial for cardiovascular health.
  • This study investigates determinants of coronary artery alterations.

Purpose of the Study:

  • To identify factors associated with coronary artery atherosclerosis and ectasia.
  • To compare patient characteristics across normal, atherosclerosis, and ectasia groups.
  • To elucidate the relationship between systemic diseases and coronary artery morphology.

Main Methods:

  • 127 patients were assessed for baseline characteristics, echocardiography, and lab values.
  • Patients were categorized into normal (N), atherosclerosis (A), and ectasia/aneurysm (E) groups.
  • Non-parametric tests (Mann-Whitney U, Kruskal Wallis) analyzed data.

Main Results:

  • Diabetes mellitus, hypertension, and chronic kidney disease were more prevalent in the atherosclerosis group (Group A).
  • The mean TAPSE/sPAP ratio was lower in Group A compared to Group E and normal individuals.
  • Vasculitis was more frequent in Group E; musculoskeletal diseases were higher in Groups A and E than Group N.

Conclusions:

  • No specific risk factors were identified for coronary artery ectasia.
  • Diabetes mellitus, hypertension, chronic kidney disease, and low ejection fraction are significantly associated with coronary artery atherosclerosis.
Abstract

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