Partial ampullary endoscopic mucosal resection in patients with difficult biliary cannulation: a prospective cohort...

Area of Science:

• Gastroenterology
• Endoscopic Surgery
• Biliary Interventions

Background:

• Limited effective rescue techniques exist for biliary cannulation failure.
• Partial ampullary endoscopic mucosal resection (PA-EMR) has emerged as a novel approach for challenging biliary cannulation.

Purpose of the Study:

• To evaluate the efficacy and safety of PA-EMR in a larger cohort of patients experiencing difficult biliary cannulation.
• To assess PA-EMR as a rescue strategy for ERCP-related cannulation challenges.

Main Methods:

• A prospective cohort study was conducted at a tertiary care referral hospital.
• Data collected included patient demographics, procedural details, and adverse event rates for patients undergoing PA-EMR for difficult biliary cannulation.
• The study included 40 patients between June 2021 and June 2022.

Main Results:

• 100% technical success rate was achieved with PA-EMR, with no patients requiring repeat procedures.
• No adverse events or 30-day mortality were reported in the study cohort.
• The primary indications for PA-EMR were bile duct stones (60%) and periampullary tumors (15%).

Conclusions:

• PA-EMR is a highly effective and safe rescue technique for managing difficult biliary cannulation.
• This method provides a reliable solution for challenging ERCP procedures, improving patient outcomes.