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A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
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Published on: August 18, 2015

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Stroke in the pediatric intensive care unit

Javier Zorrilla Abad1, Débora Sanz Álvarez2, Gema Manrique Martín2

  • 1Departamento de Salud Pública y Maternoinfantil, Facultad de Medicina, Universidad Complutense de Madrid, Madrid, Spain.

Medicina Intensiva
|February 25, 2025
PubMed

Insights

Pediatric stroke, particularly ischemic stroke, is more common than hemorrhagic stroke. Children experiencing stroke face high mortality and significant long-term neurological deficits, especially those with heart conditions or on ECMO.

Area of Science:

  • Pediatric Neurology
  • Critical Care Medicine
  • Epidemiology

Background:

  • Stroke in children is a critical neurological event with significant morbidity and mortality.
  • Understanding the specific characteristics of pediatric stroke is essential for improving patient outcomes.

Purpose of the Study:

  • To investigate the incidence, causes, risk factors, mortality, and sequelae of stroke in pediatric patients admitted to the pediatric intensive care unit (PICU).

Main Methods:

  • A single-center retrospective observational study utilizing a prospective database.
  • Inclusion criteria: Children aged one month to 18 years diagnosed with stroke and admitted to the PICU.
  • Data collected included epidemiological, clinical, diagnostic, treatment, sequelae, and mortality information.

Main Results:

  • Ischemic stroke (63%) was more frequent than hemorrhagic stroke (30.4%) among 46 pediatric patients.
  • Mortality was 19.6%, with higher rates in patients with heart disease or treated with extracorporeal membrane oxygenation (ECMO).
  • Over 62% of survivors experienced sequelae, most commonly hemiparesis, particularly in those with motor symptoms.

Conclusions:

  • Ischemic stroke is more prevalent than hemorrhagic stroke in pediatric patients.
  • Pediatric stroke is associated with high mortality and a substantial rate of long-term sequelae.
  • Heart disease and ECMO treatment are linked to increased stroke frequency and mortality in this population.
Abstract

Keywords:
Código ictus pediátricoFibrinolisisFibrinolysisIctus pediátricoPediatric strokePediatric stroke codePrognosticPronósticoThrombectomyTrombectomía

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